Sirolimus, which is sold under the brand name Rapamune, is a drug used to intentionally lower the body's immune system defenses. As a prescription drug, Sirolimus is capable of causing a number of wide ranging side effects depending upon the dose size, the individual, and other variables.
What is Sirolimus?
Sirolimus is a prescription drug used specifically in the case of kidney transplants. By weakening the body's immune system, Sirolimus prevents the body from rejecting the kidney. The weakened immune system does not recognize the new organ as a foreign particle and therefore will not attack the organ. Recognized as an immunosuppressant, Sirolimus blocks certain blood cells that normally would reject the organ.
Common Side Effects
The use of Sirolimus may cause the following common side effects: diarrhea, acne, headache, nausea, vomiting, upset stomach, insomnia, and constipation. Although less serious, these side effects can become serious if they persist or become more bothersome. Closely monitor any side effects and contact your doctor in the case of worsening symptoms.
Serious Side Effects
Drugs.com reports that Sirolimus can cause the following serious side effects: calf pain or swelling, yellowing of the skin, vision changes, unusual; weight change, irregular heartbeat, irregular urination, chest pain, mood changes, severe skin irritation and rash, muscle pain, difficulty breathing, swelling of the extremities, easy bleeding or bruising, weakness, tremors, skin growths, and severe allergic reaction including swelling of the face or throat. These side effects are severe and should be treated seriously. Seek immediate medical attention in the occurrence of any of the preceding side effects.
Use Sirolimus
Take Sirolimus exactly as prescribed to you by your doctor so that the dose size or duration of the medication is never altered. This medication should be taken with a full glass(8 oz.) of water. You may take Sirolimus with or without food, but never crush or chew the tablet so as to avoid an inappropriate release of the drug. If using Sirolimus in liquid form, mix with a 1/4 cup of water. Take once per day.
Warning
Avoid grapefruit and grapefruit juice as they interact with the medication in a harmful way. Because Sirolimus intentionally lowers the body's immune system, avoid people with the common cold or flu-like symptoms. Never take a double dose of Sirolimus to compensate for a missed or skipped dose. Avoid skin exposure to the sun as Sirolimus can increase the risk for skin cancer. Sirolimus should never be used in the cases of lung or liver transplants.
Tags: immune system, side effects, body immune, body immune system, side effects